1357 On April - 22 birth of johan I, King of Portugal (1383-1433)
1451 On this day in history birth of isabella I, of Castile, Queen of Spain (1479-1504), patron of Columbus
1610 On this day in history birth of alexander VIII, [Pietro Ottoboni], Italy, lawyer/Pope (1689-91)
1640 On this day in history birth of mariana Alcoforado, Portugal, nun
1658 On April - 22 birth of giuseppe Torelli, Italy, composer (Concert Grossi op 8)
1682 On April - 22 birth of willem I Kerricx the Young, Flemish architect/sculptor/painter
1690 John Carteret, Earl Granville (C), English chief minister (1722-42) was born on this day in history.
1692 On this day in history birth of james Stirling, Scottish mathematician (d. 1770)
0296 Death of Pope Caius on this day in history.
0536 On April - 22 agapitus I, Italian Pope (535-36), dies
1253 On this day in history elias van Cortona, Italian general (1232-39), dies at about 53
1355 On April - 22 eleonora Plantagenet, daughter of King Edward II, dies at 36
1462 On April - 22 gilbert of Lannoy, master of Villerval/Tronchiennes/Santes, dies
1521 Death of Juan de Padilla, Spanish nobleman/communero-rebel, beheaded on this day in history.
1592 Bartolommeo Ammanati, Italian sculptor/architect, dies at 80 on this day in history.
1648 On this day in history catharina Belgian van Nassau, daughter of Willem, dies at 69