1357 Johan I, King of Portugal (1383-1433) was born on this day in history.
1451 On this day in history birth of isabella I, of Castile, Queen of Spain (1479-1504), patron of Columbus
1610 On April - 22 birth of alexander VIII, [Pietro Ottoboni], Italy, lawyer/Pope (1689-91)
1640 Mariana Alcoforado, Portugal, nun was born on April - 22.
1658 On this day in history birth of giuseppe Torelli, Italy, composer (Concert Grossi op 8)
1682 On April - 22 birth of willem I Kerricx the Young, Flemish architect/sculptor/painter
1690 John Carteret, Earl Granville (C), English chief minister (1722-42) was born on this day in history.
1692 On April - 22 birth of james Stirling, Scottish mathematician (d. 1770)
0296 On this day in history death of pope Caius
0536 On this day in history agapitus I, Italian Pope (535-36), dies
1253 On April - 22 elias van Cortona, Italian general (1232-39), dies at about 53
1355 On this day in history eleonora Plantagenet, daughter of King Edward II, dies at 36
1462 Gilbert of Lannoy, master of Villerval/Tronchiennes/Santes, dies on April - 22.
1521 On this day in history death of juan de Padilla, Spanish nobleman/communero-rebel, beheaded
1592 On April - 22 bartolommeo Ammanati, Italian sculptor/architect, dies at 80
1648 On April - 22 catharina Belgian van Nassau, daughter of Willem, dies at 69